Treatment Strategies in Primary Vitreoretinal Lymphoma

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Treatment strategies in primary vitreoretinal lymphoma: a 17-center European collaborative study.

IMPORTANCE The best treatment option for primary vitreoretinal lymphoma (PVRL) without signs of central nervous system lymphoma (CNSL) involvement determined on magnetic resonance imaging or in cerebrospinal fluid is unknown. OBJECTIVE To evaluate the outcomes of treatment regimens used for PVRL in the prevention of subsequent CNSL. DESIGN, SETTING, AND PARTICIPANTS A retrospective cohort s...

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Primary Vitreoretinal Lymphoma Masquerading as Refractory Retinitis

PURPOSE To report a case of a patient with primary vitreoretinal lymphoma masquerading as retinitis. METHODS Retrospective review of the patient's clinical, histopathological and imaging records. RESULTS Cytopathology was negative for malignancy, and preliminary polymerase chain reaction results supported the diagnosis of varicella zoster virus retinitis. Therefore, the patient was treated ...

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Subretinal pigment epithelial infiltrates in primary vitreoretinal lymphoma

A 67-year-old woman with chronic bilateral intraocular inflammation associated with vitreous cells and subretinal pigment epithelium (RPE) infiltrates (A–B) underwent a chorioretinal biopsy in the left eye after three negative vitreous biopsies. Sub-RPE deposits on spectral domain optical coherence tomography (C) corresponded to collections of diffuse large B-cell lymphoma cells on histopathogy...

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Recent progress in the diagnosis and treatment of primary vitreoretinal lymphoma

Primary vitreoretinal lymphoma (PVRL) was previously termed primary intraocular lymphoma. PVRL is a potentially fatal intraocular malignancy, and 65-90% of PVRL cases eventually involve the central nervous system (CNS). The incidence of PVRL has been rising in both immunocompromised and immuno-competent populations worldwide. PVRL frequently masquerades as chronic uveitis. Advanced auxiliary ex...

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Multimodal Imaging of Spontaneously Shifting Primary Vitreoretinal Lymphoma.

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ژورنال

عنوان ژورنال: JAMA Ophthalmology

سال: 2015

ISSN: 2168-6165

DOI: 10.1001/jamaophthalmol.2014.4755